A Secret Weapon For https://www.ceesdekker.net
A Secret Weapon For https://www.ceesdekker.net
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Using one-molecule optical and AFM imaging and pressure-spectroscopy tactics, we seek out to unravel the mechanistic elements of the structure and dynamics of chromosomes. Our research pursuits include things like:
1996, to start with mesoscopic charge density waves products; and initial electrical measurements on one metallic nanocluster among nanoelectrodes
[Laughs] ‘It had been absolutely a terrific chance! At enough time, I used to be nicely conscious that it could go Incorrect and that I could come to be significantly less prosperous, but I just overlooked that. Curiosity has often been my strongest driving power. And luckily everything labored out.’
A rhythmically pulsing leaf-spring DNA-origami nanoengine that drives a passive follower Mathias Centola
That is a aspiration of mine and we established to work that has a delicious dose of naivety. That is a thing that will probably produce amazing results in the more time time period, but that does not subject. You shouldn't only want to work about the thoughts of tomorrow, but additionally about the thoughts from the day immediately after tomorrow.’
Microbiology has only existed to get a century, considering that we began to review micro-organisms extra very seriously. I thought nanobiology was an appropriate term, since all molecular biological appropriate interactions happen with the nanoscale: a protein is a couple of nanometres in measurement, DNA is 2 nm thick.’
‘At the outset we checked out biological techniques which has a physical check out and acted on The idea of your resources we understood. It took a number of years prior to we started out Performing more on the big biological problems. I then started to phone it nanobiology, a time period that didn't exist at the time.
Nanopores symbolize an elegant and flexible Instrument to measure single molecules. We study novel detection modes with strong-state nanopores in addition to numerous approaches to measure cees dekker proteins with nanopores. Projects encompass the following:
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Bulk-floor coupling identifies the mechanistic relationship between Min-protein patterns in vivo and in vitro
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Character Physics thanks the nameless reviewers for their contribution to your peer overview of this get the job done.
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Illustration (2) of bending configurations in 3D simulations of DNA rods on nanopores. A part of the membrane is shown in grey, the rim of the pore is highlighted in purple, along with a 3D rendering with the motion with the DNA rod is shown.